The Emerging Role of The Eosinophil and Its Measurement in Chronic Cough
Mahboobeh H. Sadeghi, Alyn H. Morice*
Identifiers and Pagination:Year: 2017
First Page: 17
Last Page: 30
Publisher Id: TORMJ-11-17
Article History:Received Date: 07/04/2017
Revision Received Date: 29/04/2017
Acceptance Date: 08/05/2017
Electronic publication date: 30/06/2017
Collection year: 2017
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Although the aetiology of chronic cough in guidelines is clearly stated as asthma and related syndromes, gastro-oesophageal reflux disease (GORD), and upper airways disease, the inflammatory mechanisms underlying these conditions differ. Recent studies on asthma have increasingly focused on its molecular phenotypes instead of clinical characteristics. Here, we proposed the hypothesis that divides cough into two groups; the eosinophilic and neutrophilic. This division will enhance our ability to recognise the type of airway inflammation which, as a consequence will lead us to more targeted and personalized treatment approaches.