Spirometric Values of Greek People and Comparison with ECSC and GLI Values in COPD People

Nikolaos Tatsis1, *, Sotirios Kakavas1, Evgenios Metaxas1, Evangelos Balis1, George Tatsis1, Nikolaos Pantazis2, Petros Bakakos3, Nikolaos Koulouris3, Κostantinos Hadjistavrou3
1 Pulmonary Department of EVAGGELISMOS Hospital, Athens, Greece
2 Department of Hygiene, Epidemiology & Medical Statistics, Athens University Medical School,Athens, Greece
3 1st Respiratory Medicine Department, National and Kapodistrian University of Athens Medical School, ‘’SOTIRIA” Hospital for Diseases of the Chest, Athens, Greece

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Creative Commons License
© 2018 Tatsis et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: ( This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the Pulmonary Department of EVAGGELISMOS Hospital, Athens, Greece; Tel: 30 69 4465 59 68; E-mail:



During the past few years, the use of criteria introduced by Global Initiative for Chronic Obstructive Lung Disease (GOLD) is recommended for the diagnosis and classification of Chronic Obstructive Pulmonary Disease(COPD),taking into account the values of a Forced Expiratory Volume In 1 second (FEV1) and a Forced Expiratory Volume In 1 second (FEV1) to Forced Vital Capacity (FVC) ratio. In Europe, the reference values of the European Coal and Steel Community (ECSC), that were originally developed in 1993 are still used.

Aim of the Study:

The study aimed to carry out measurement of spirometric values in a healthy, non smoking Greek population, development of local equations and comparison with ECSC and Global Lung Initiative(GLI) equations, in order to see if there is a need for separate ones in everyday use.


Normal predicted values for FEV1 and FEV1/FVC% were obtained from a group of 500 healthy subjects, aged 18-89 years. In addition, a group of 124 COPD patients, with no other comorbidities was studied. Patients were classified according to GOLD criteria in four groups with ECSC, GLI predicted values or with our own predicted values.


The statistical analysis has revealed that there is no significant difference among the three sets of predicted values and no statistical difference was detected among the classification of COPD patients.


It is shown that the 3 sets of predicted values are almost identical, despite the fact that they have been collected from different study populations.Αccording to the study, there is no need in recalculating values for Greek population.

Keywords: COPD, GOLD classification, GLI equations, ECSC equations, FVC, FEVI.