Aims and Scope
Tracheostomy-related Tracheal Tears in PediatricsMazyad Alenezi, Ali Alsudays, Sultan Alanazy, Eman Almashharawi and Samir Bawazir
The Open Respiratory Medicine Journal, 2022; 16: e187430642209290.
Electronic Publication Date: December 30, 2022
Bronchoscopy Findings of Severe and Critical COVID-19 Patients Treated in ICU: A Year of Experience in a Developing CountryIrandi Putra Pratomo, Gatut Priyonugroho, Hario Baskoro, R.R. Diah Handayani, Jamal Zaini, Anna Rozaliyani, Dita Aditianingsih, Ardiana Kusumaningrum, Tutug Kinasih, Ike Maretta and Himela Asfi Rasigita
The Open Respiratory Medicine Journal, 2022; 16: e187430642210210.
Electronic Publication Date: December 16, 2022
Acute Pericarditis as the Primary Presentation of COVID-19 Infection followed by Guillain-Barre Syndrome in a Healthy Young Man: A Case ReportGiti Noghabaei, Maliheh Arab, Sara Payami and Behnaz Ghavami
The Open Respiratory Medicine Journal, 2022; 16: e187430642210190.
Electronic Publication Date: December 12, 2022
Lack of Benefit of High Flow Nasal Oxygen Therapy as Ceiling of Treatment for Severe COVID-19 Pneumonitis in Elderly Frail Patients: A Single Centre Observational StudyFatema Merchant, Akash Mavilakandy, Harvinder S. Virk, Sajid Khan, Georgios Tsaknis, Muhammad Naeem, Srikumar Mallik, Kirsty Datson and Raja Reddy
The Open Respiratory Medicine Journal, 2022; 16: e187430642206271.
Electronic Publication Date: October 19, 2022
IgE Mediated Wheat Allergy Associated with Resistant and Severe Forms of Allergic ConjunctivitisKhulood M. Sayed and Abdellah H. Ali
The Open Respiratory Medicine Journal, 2022; 16: e187430642208170.
Electronic Publication Date: October 10, 2022
Outcomes of Continuous Positive Airway Pressure in the Management of Patients with Coronavirus (COVID-19) Pneumonia who are not Suitable for Invasive VentilationHnin Aung, Eleni Avraam, Muhammad Ashraf, Nawazish Karim, Sidra Kiran, Muhammed Naeem, Srikumar Mallik, Selva Panchatsharam, George Tsaknis, Raja Reddy
The optimum management of respiratory failure in patients with coronavirus (COVID-19) infections has been a challenge for physicians across the globe. Many scientific societies have suggested the use of CPAP (continuous positive airway pressure) in severe cases in an effort to reduce invasive ventilation. We investigated mortality outcomes in patients who needed CPAP but were not suitable for invasive ventilation.
We retrospectively evaluated the mortality outcomes of all consecutive COVID-19 cases with severe type 1 respiratory failure requiring FiO2 >0.6 who were admitted to our hospital between 12th March and 04th May’20. British Thoracic Society guidelines were followed for identifying patients needing CPAP. Their outcomes were recorded and compared with a similar group of patients who had oxygen as a ceiling of care. Prospectively collected data between 5th May and 7th June’20 in similar but smaller groups of patients was also analyzed.
A total of 104 COVID-19 patients with documented Do Not Attempt Resuscitation (DNAR) decision required high fraction of inspired oxygen (FiO2) >0.6(to maintain peripheral oxygen saturation (SpO2)> 92%(SpO2> 88% in COPD patients). Twenty-four patients received CPAP as the ceiling of care, with a mortality rate of 92.5%. The remaining 84 patients who were on oxygen as a ceiling of treatment had 91.7% mortality. Both population groups had a similar number of comorbidities but were less favorable in terms of age in the control group with standard O2 therapy than those who had CPAP support. Overall mortality outcomes from using CPAP therapy did not bring significant mortality benefit (p-value-0.89).
CPAP did not appear to improve the survival of patients with severe respiratory failure due to COVID-19 related pneumonia and were not suitable for invasive ventilation. Further studies are warranted to adequately inform appropriate management strategies for this group of patients.
June 18, 2021
- December 18, 2020
Weaning from Mechanical Ventilator in a Long-term Acute Care Hospital: A Retrospective AnalysisDecember 27, 2017
Evaluation of Breath-Holding Test in Assessment of Peripheral Chemoreflex Sensitivity in Patients with Chronic Heart FailureMay 29, 2017
24-Hour Hypoxia and Pulmonary Hypertension in Patients with Idiopathic Pulmonary FibrosisJune 30, 2017
The Emerging Role of The Eosinophil and Its Measurement in Chronic CoughJune 30, 2017
Survival of Hypercapnic Patients with COPD and Obesity Hypoventilation Syndrome Treated with High Intensity Non Invasive Ventilation in the Daily Routine CareJuly 25, 2017
Bronchodilator Response Assessment of the Small Airways Obstructive Pattern